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Poppers or nitrate inhalants, surfaced as a popular recreational high. They give the user a “buzz” and can facilitate anal sex. Amyl nitrite is in a small mesh-covered glass container that is popped or snapped to release the vapors.

However, nitrate chemicals are highly toxic and cause many health problems, such as severe headaches that do not go away, severe vomiting, people go into seizure, and some die instantly.